PHYS THER
Vol. 89, No. 10, October 2009, pp. 1098-1099
DOI: 10.2522/ptj.2009.89.10.1098
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Letters and Responses

On "A guide to interpretation of studies..." Hancock M, et al. Phys Ther. 2009;89:698–704.


Because this article has no abstract, we have provided an extract of the full text and any section headings.

I read with interest and some puzzlement the article titled "A Guide to Interpretation of Studies Investigating Subgroups of Responders to Physical Therapy Interventions" by Hancock et al1 in the July 2009 issue of PTJ. In their article, these authors expressed the opinion that treatment-related clinical prediction rules (CPRs) are flawed when derived using single-arm studies. The single-arm research design has been used for virtually all published CPRs in this category, so the implication seems to be that all currently published CPR derivations of this type are inherently flawed.

These authors drew distinctions among treatment effect modifiers, prognostic factors, and diagnostic tests. They asserted that although a single-arm research design is appropriate for prognostic and diagnostic studies, this design . . . [Full Text of this Article]

Stephen C. Allison

S.C. Allison, PT, PhD, is Professor, Rocky Mountain University of Health Professions, and Associate Professor, Baylor University.


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M. Hancock, R. Herbert, and C. G. Maher
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Physical Therapy, October 1, 2009; 89(10): 1099 - 1100.
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